This study focuses on study members without any prior heart diagnosis. By conducting baseline or event-triggered MRI heart assessments, researchers aim to create a detailed profile of normal heart health and its variance over time. Study members may optionally undergo whole genome sequencing and immune profiling, depending on their MRI results. The primary goal is to understand how genetics and immune system variability influence heart function in healthy individuals over time.
This study focuses on study members who have been previously diagnosed with heart disease. The MRI heart assessment is used to track changes in heart health over time, while optional whole genome sequencing and immune profiling may be conducted based on the MRI findings. The study focuses on understanding how immune and genomic factors contribute to the progression of heart disease and how these insights can guide improved heart health strategies.
This study is designed for study members who are postmenopausal women with RA who are receiving biologic therapy. The MRI heart assessment looks to identify the impact of treatment on the heart, while optional immune and genomic profiling may be conducted to explore how RA treatment influences heart health. The goal is to better understand the connection between immune responses from RA treatment and heart health, potentially informing future heart health management strategies.
This study is open to study members who are young athletes, this study utilizes MRI heart assessments to detect subclinical cardiac conditions that may affect athletic performance or increase the risk of heart health events. Immune and genomic profiles may be added optionally based on the MRI results. The study aims to help identify heart anomalies early on in athletes, allowing for interventions that could prevent future health issues during high-intensity activities.